Estronex Profile

Estronex Profile is a great tool to identify patients with imbalanced estrogen levels related to good vs bad estrogens and the health conditions to which bad estrogen can contribute. As an example, assessment of the little known 2:16 alpha hydroxyestrone ratio identifies those who might benefit from a nutritional treatment plan to help the body metabolize these estrogens out of the body and return the ratio back to normal.

The Estronex Profile is a home estrogen test that measures six important estrogen metabolites and their ratios to help women and men, assess their risk of developing estrogen sensitive cancers.

The Estrogen Profile can be used to assess the risk of estrogen sensitive cancers such as uterine, ovarian, cervical, prostate, and head and neck cancers. Many inflammatory conditions also have hormone connections that may be directly related to the improper ratio of 2:16 alpha hydroxyestrone.

These inflammatory condition include Addison’s Disease, Amyotrophic Lateral Sclerosis (Lou Gehrig’s Disease), Hashimoto’s thyroiditis, Crohn’s Disease, all types of colitis, arthritis, rheumatoid arthritis (RA), psoriatic arthritis, Multiple Sclerosis, Meniere’s disease, myasthenis gravis, Raynaud’s disease, fibromyalgia, Sjogren’s Syndrome, lupus, scleroderma, ankylosing spondylitis, interstitial cystitis, depression, asthma, heart disease, diabetes, Alzheimer’s and osteoporosis

The Estronex Profile measures six important estrogen metabolites, and ratios, including:

The “Good” Estrogen

2-hydroxyestrone (2-OHE1) – high levels of 2-OHE1 are ideal to reduce cancer growth.
2-hydroxyestradiol (2-OHE2) – shown to exhibit anti-carcinogenic effects.
2-methoxyestrone (2-OMeE1) – OMeE1 has shown to have anticancer effects and is ideal in high levels.
4-methoxyestrone (4-OMeE1) – as a non-cancerous metabolite, OMeE1 generally does not require treatment at high levels in the body.

The “Bad” Estrogen

4-hydroxyestrone (4-OHE1) – considered a “bad” estrogen, 4-OHE1 levels should be low
16-α-hydroxyestrone (16α-OHE1) – also considered a “bad” estrogen, 16α-OHE1 in high levels may encourage tumor development.

The Ratios

2-OHE:16α-OHE1 (2:16 ratio) – 2:16 ratios less than 2.0 indicate increasing long-term risk for breast, cervical, and other estrogen sensitive cancers and inflammatory conditions.
2-OHE1:2-OMeE1 – a high level of 2-OHE1:2-OMeE1 may also indicate imbalanced estrogen metabolism.

Advantages of the Estronex Profile:

An easy-to-collect first-morning urine specimen; no blood draw is necessary.
Cost-effective method to assess estrogen metabolism allowing clinicians to retest often to monitor therapy in patients.
Easy to incorporate into a breast cancer prevention program.
Ideal for men to evaluate risk of breast and prostate cancer.
A great way to reduce the inflammatory process in estrogen mediated inflammatory conditions.